Establishment and application of drug use evaluation criteria for aspirin enteric-coated tablets
10.12173/j.issn.1005-0698.202312012
- VernacularTitle:阿司匹林肠溶片药物利用评价标准的建立与应用
- Author:
Meimei LIN
1
;
Jing ZHANG
;
Caiyun ZHENG
;
Yan CHEN
;
Yanling GAO
;
Shicai CHEN
;
Jinhua ZHANG
Author Information
1. 福建医科大学附属福清市医院药剂科(福建福清 350300)
- Keywords:
Aspirin enteric-coated tablets;
Drug use evaluation;
Expert consultation;
Rational drug use
- From:
Chinese Journal of Pharmacoepidemiology
2024;33(5):489-499
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish the drug use evaluation(DUE)criteria for aspirin enteric-coated tablets and provide a reference for the rationally clinical application of aspirin enteric-coated tablets.Methods DUE criteria for aspirin enteric-coated tablets were established from three aspects of indications,medications and medication results with reference to drug instructions of aspirin enteric-coated tablets,related guidelines,expert consensus and literature,and through Delphi method.A retrospective analysis was conducted to evaluate the medical records of patients who took aspirin enteric-coated tablets from January 2021 to June 2022 in Fuqing Hospital affiliated to Fujian Medical University.Results A total of 1 071 medical records were included.683 cases fully met the DUE criteria,with a rational rate of 63.77％.Irrational drug use mainly included inappropriate indications(6.26％),off-label drug use without approval(28.48％),contraindications(1.03％),inappropriate usage and dosage(1.68％),drug interactions with potential clinical significance(0.65％)and other inappropriate drug use(2.71％).Conclusion The established DUE standard for aspirin enteric-coated tablets has strong scientific practicability and feasibility.The irrational rate of aspirin enteric-coated tablets in this hospital is high.Corresponding intervention measures should be formulated to ensure the safety of clinical medication.
