A comparative study on recurrent stroke caused by cerebral microbleed or asymptomatic lacunar infarction
10.3760/cma.j.cn115455-20230722-00022
- VernacularTitle:脑微出血和无症状腔隙性脑梗死引起再发卒中的比较研究
- Author:
Yanjie ZHANG
1
;
Xiaopan LIU
;
Deqin GENG
;
Chuanhui ZHANG
;
Yanqiang WANG
Author Information
1. 徐州医科大学研究生院，徐州 221004
- Keywords:
Cerebral microbleeds;
Asymptomatic lacunar infarction;
Recurrent stroke;
Risk factors
- From:
Chinese Journal of Postgraduates of Medicine
2024;47(12):1064-1067
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the risk of new-onset stroke caused by cerebral microbleed (CMB) and asymptomatic lacunar infarction (ALI) and their risk factors.Methods:A prospective observational study over a 18 month period was conducted on 397 non stroke patients who visited the Affiliated Hospital of Xuzhou Medical University from March 2020 to June 2022. By the presence of CMB and ALI about magnetic resonance imaging, they were divided into th control group (without CMB and ALI, 117 cases, 29.5%), ALI group (101 cases, 25.4%), CMB group (89 cases, 22.4%) and CMB-ALI group (90 cases, 22.7%).They were followed up for 18 months, the risk factors for CMB, ALI, and the risk of new stroke were analyzed.Results:The systolic blood pressure and uric acid in the CMB group were higher than those in the control group: (155.2 ± 24.2) mmHg(1 mmHg = 0.133 kPa) vs. (138.2 ± 19.0) mmHg, (387.0 ± 28.3) μmol/L vs. (354.0 ± 21.5) μmol/L, there were statistical differences ( P<0.05). After followed up for 18 months, the incidence rate of cerebral infarction, cerebral hemorrhage and TIA in the CMB group and CMB-ALI group were higher than those in the control group: 13.5%(12/89), 13.3%(12/90) vs.5.1%(6/117); 9.0%(8/89), 10.0%(9/90) vs. 2.6%(3/117); 5.6%(5/89), 6.7%(6/90) vs. 0.8%(1/117), there were statistical differences ( P<0.05). Conclusions:CMB is prone to abnormal systolic blood pressure and uric acid. CMB, CMB-ALI are prone to new onset ischemic stroke, cerebral hemorrhage and TIA.
