Nutritional risk screening for elderly patients with colorectal cancer and its impact on infectious complications
10.3760/cma.j.cn115455-20240112-00051
- VernacularTitle:老年结直肠癌患者营养风险筛查及其对术后感染性并发症的影响
- Author:
Hui JIAO
1
;
Yongjing DAI
;
Teng MA
;
Xueqiong MA
Author Information
1. 解放军总医院第一医学中心普通外科医学部，北京 100853
- Keywords:
Colorectal neoplasms;
Aged;
Nutritional status;
Infectious complications
- From:
Chinese Journal of Postgraduates of Medicine
2024;47(10):940-944
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the nutritional status of elderly patients with colorectal cancer and its impact on postoperative infectious complications.Methods:A retrospective collection was conducted on 782 colorectal cancer patients admitted to the First Medical Center of PLA General Hospital from June 2020 to June 2022. The nutritional status of the patients was screened, and they were divided into nutritional risk group (355 cases) and control group (427 cases) based on whether they had nutritional risk. The main clinical characteristics and postoperative recovery of the two groups were compared. The predictive value of nutritional related indicators for postoperative infectious complications was also analyzed.Results:Univariate analysis showed that age, tumor invasion of intestinal wall muscle layer and decreased serum albumin were risk factors for nutritional risk in elderly patients with colorectal cancer ( P<0.05). The results of multivariate factor analysis showed that age≥75 years old was an independent risk factor for nutritional risk in elderly patients with colorectal cancer ( RR = 1.990, 95% CI 1.402 - 2.825, P<0.01). Compared with the control group, patients in the nutrition risk group had longer hospital stay and an increased incidence of postoperative complications: (13.59 ± 8.20) d vs. (11.91 ± 5.04) d, 16.34%(58/355) vs. 6.09%(26/427), there were statistical differences ( P<0.05). The results of multivariate factor analysis showed that elderly nutrition risk index<98, preoperative chemotherapy were risk factors for infectious complications in colorectal cancer patients ( RR = 2.982, 95% CI 1.818 - 4.890, P<0.01; RR = 2.759, 95% CI 1.119 - 6.799, P<0.05). Conclusions:The proportion of elderly patients with colorectal cancer who have nutritional risk is relatively high, and age is the main factor leading to nutritional risk. Nutritional risk can lead to an increase in postoperative infectious complications.
