Influence of OSAHS on nocturnal blood pressure and angina pectoris in patients undergoing cardiac artery bypass graft
10.3760/cma.j.cn115682-20191031-03939
- VernacularTitle:合并OSAHS对冠状动脉旁路移植术患者夜间血压及心绞痛的影响
- Author:
Yuan HE
1
;
Yuan LIU
;
Lipeng ZHANG
;
Yaqiong ZHANG
;
Yanqi XU
;
Xiumei CHEN
;
Xuemei LI
Author Information
1. 首都医科大学附属北京安贞医院心脏外科 100029
- Keywords:
Sleep apnea, obstructive;
Coronary artery bypass;
Sleep respiratory monitoring;
Blood pressure;
Angina pectoris
- From:
Chinese Journal of Modern Nursing
2020;26(21):2853-2857
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the influence of obstructive sleep apnea hypopnea syndrome (OSAHS) on nocturnal blood pressure and angina pectoris in patients undergoing cardiac artery bypass graft (CABG) .Methods:From January to December 2018, we selected 76 patients with simple CABG at Beijing Anzhen Hospital affiliated to Capital Medical University by purposive sampling. Before surgery, patients were treated with the portable sleep respiratory monitoring and bedside blood pressure monitoring. Patients were divided into group of mild or no OSAHS ( n=35) and group of moderate or severe OSAHS ( n=41) based on apnea hypopnea index (AHI) . We compared the differences in the baseline data, sleep respiratory examination indexes, nocturnal angina pectoris, blood pressure at 21∶00, 3∶00 and 6∶00 among patients between two groups. Results:Among CABG patients with moderate or severe OSAHS, the systolic pressure at 3∶00 and 6∶00 was (115.8±12.5) mmHg and (156.8±17.5) mmHg respectively all higher than those among CABG patients with mild or no OSAHS with statistical differences ( P<0.05) ; the incidence of nocturnal angina pectoris was 29.27% (12/41) higher than that [2.86% (1/35) ]among CABG patients with mild or no OSAHS with a statistical difference ( P<0.05) . Logistic regression analysis showed that the systolic pressure at 3∶00 could affect the occurrence of nocturnal angina pectoris among CABG patients with OSAHS ( OR=1.050, 95% CI 1.003-1.100, P=0.039) ; the decrease of average oxygen saturation could also affect the occurrence of nocturnal angina pectoris among those patients ( OR=0.628, 95% CI 0.397-0.993, P=0.046) ; the differences were all statistical. Conclusions:Early morning systolic pressure of CABG patients with OSAHS raises, and OSAHS may increase the incidence of nocturnal angina pectoris among CABG patients.