Synchronous double primary cancers associated with a choledochal cyst and anomalous pancreaticobiliary ductal union.
10.4174/jkss.2011.81.4.281
- Author:
Kang Kook CHOI
1
;
Sae Byeol CHOI
;
Seung Woo PARK
;
Hyun Ki KIM
;
Young Nyun PARK
;
Kyung Sik KIM
Author Information
1. Department of Surgery, Yonsei University College of Medicine, Seoul, Korea. kskim88@yuhs.ac
- Publication Type:Case Report
- Keywords:
Choledochal cyst;
Gallbladder neoplsms;
Bile duct neoplasms;
Synchronous multiple primary neoplasms
- MeSH:
Bile Duct Neoplasms;
Choledochal Cyst;
Colon;
Common Bile Duct;
Constriction, Pathologic;
Female;
Gallbladder;
Gallbladder Neoplasms;
Humans;
Middle Aged;
Neoplasms, Multiple Primary;
Pancreas;
Pancreaticoduodenectomy;
Recurrence;
Seeds
- From:Journal of the Korean Surgical Society
2011;81(4):281-286
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 60-year-old female was admitted with epigastric pain lasting a month. Preoperative diagnosis was choledochal cyst with anomalous pancreaticobiliaryductal union (APBDU), C-P type. A papillary mass measuring 2.5 x 1.9 cm was found adjacent to the pancreaticocholedochal junction. Gallbladder (GB) cancer was also observed. Pyloric-preserving pancreaticoduodenectomy (PPPD) was performed. The patient received adjuvant chemotherapy/radiation therapy on the tumor bed. The gallbladder cancer showed serosal invasion, while the bile duct cancer extended into the pancreas. Although common bile duct (CBD) cancer lesion showed focally positive for p53 and the gallbladder cancer lesion showed negative for p53, the Ki-67 labeling index of the CBD cancer and GB cancer were about 10% and 30%, respectively. Nine months after curative resection, a stricture on the subhepatic colon developed due to adjuvant radiation therapy. Localized peritoneal seedings were incidentally found during a right hemicolectomy. The patient underwent chemotherapy and had no evidence of tumor recurrence for two years after PPPD.
