Study on micro wave ablation of lung tumor based on real anatomical model
10.19745/j.1003-8868.2024169
- VernacularTitle:基于真实解剖模型的肺肿瘤微波消融研究
- Author:
Ju LIU
1
;
Hong-Jian GAO
;
Qi WANG
;
Yu-Bo ZHANG
;
Hui-Jing HE
;
Wei-Wei WU
;
Shui-Cai WU
Author Information
1. 北京工业大学化学与生命科学学院,北京 100124
- Keywords:
tumor treatment;
lung tumor;
microwave ablation;
real anatomical structure;
simulation analysis
- From:
Chinese Medical Equipment Journal
2024;45(9):27-34
- CountryChina
- Language:Chinese
-
Abstract:
Objective To plan microwave antenna puncture direction effectively and realize personalized preoperative simulation by exploring microwave ablation(MWV)outcomes of lung cancer based on real anatomical model.Methods Firstly,a personalized MWA simulation model consisting of the lung tissue,tumor and vascular system was constructed based on the lung CT data of real patients.Secondly,the MWA effect was simulated by coupling 2 physical fields including an electromagnetic field and a biological heat transfer field,so as to determine the volume of the ablation thermocoagulation zone and the temperature distribution of the lung tissue.Finally,the effects of the vascularized network on the ablation results were quantitatively evaluated in terms of conductivity and blood perfusion,and the ablation results were analyzed with different distances between the large vessels and the antennae(5 and 10 mm from the antennae tips)and puncture angles(large vessels parallelling or intersecting with the antennae tips).Results The vascularized network reduced the volume of the thermocoagulation zone by 0.5％to 3.7％,and blood perfusion made the ablation temperature and the volume of the thermocoagulation zone decreased significantly.The cooling effect gradually diminished with the increase of the distance between the large vessels and the antenna.With the same treatment parameters,the thermocoagulation zone formed when the large vessels paralleled with the antenna was obviously larger than that when the vessles intersected with the antenna.Conclusion Personalized MWA simulation analysis based on real CT data contributes to clarifying the temperature distribution and damage estimation close to the actual situation,which provides guidance and reference for precise treatment of the lung tumor and determination of microwave antenna puncture direction.[Chinese Medical Equipment Journal,2024,45(9):27-34]
