Application value of prognostic nutrition index to predict the quality of life in lung cancer patients undergoing palliative chemotherapy
10.3760/cma.j.cn115682-20191112-04129
- VernacularTitle:预后营养指数在姑息化疗肺癌患者生存质量预测中的应用价值
- Author:
Li WANG
1
;
Shuangning YANG
;
Chunhui WANG
Author Information
1. 郑州大学第一附属医院肿瘤内科三病区，郑州 450000
- Keywords:
Lung neoplasms;
Prognostic nutrition index;
Palliative chemotherapy;
Prognosis
- From:
Chinese Journal of Modern Nursing
2020;26(14):1880-1883
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the application value of prognostic nutrition index (PNI) in predicting the quality of life in lung cancer patients undergoing palliative chemotherapy.Methods:Totally 89 lung cancer patients who underwent palliative chemotherapy in the First Affiliated Hospital of Zhengzhou University from June 2014 to June 2017 were selected using convenient sampling, and divided into high-PNI group and low-PNI group according to PNI. The quality of life was compared between the two groups. The Kaplan-Meier method was used to draw survival curves, and Log-Rank test was employed to compare the survival rates of the two groups.Results:Two of the 89 patients died during the study period, and all data of 87 patients were completed, including 56 in the high-PNI group and 31 in the low-PNI group. The overall quality of life score of (72.44±6.49) in the high-PNI group and (68.82±6.01) in the low-PNI group, and the difference was statistically significant ( t=2.557, P<0.05) . The half-year survival rates of the high-PNI and low-PNI groups were 87.50% and 82.14%; the one-year survival rates were 81.02% and 64.28%; and the two-year survival rates were 57.73% and 39.28%, respectively. The differences in survival rates between the two groups were statistically significant (Log-Rank=4.293, P<0.05) . Conclusions:The overall quality of life in lung cancer patients undergoing palliative chemotherapy with low PNI is lower than that of high PNI patients. PNI can be used as a prognostic indicator for lung cancer patients undergoing palliative chemotherapy.
