Consistency study on reports of stomach neoplasm chemotherapy-related adverse reactions reported by different people
10.3760/cma.j.cn115682-20191006-03575
- VernacularTitle:对不同人员报告的胃癌化疗不良反应一致性研究
- Author:
Junxia WANG
1
;
Yuhua ZHAO
;
Yingying LI
;
Jiajia XING
;
Dongyan LI
Author Information
1. 郑州大学第一附属医院门诊部，郑州 450052
- Keywords:
Stomach neoplasms;
Chemotherapy;
Adverse reactions;
Main caregivers;
Nursing records;
Consistency
- From:
Chinese Journal of Modern Nursing
2020;26(13):1773-1778
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the consistency of reports of adverse reactions to chemotherapy in patients with stomach neoplasms, main caregivers and nursing records.Methods:By convenient sampling method, a total of 102 pairs of patients who underwent radical gastrectomy and received chemotherapy in the First Affiliated Hospital of Zhengzhou University from June 2018 to June 2019 and their main caregivers were selected. After the second and fourth cycles of chemotherapy, the incidence of adverse reactions to chemotherapy in patients was collected from records patients themselves, main caregivers and nursing staff, and the severity of adverse reactions was assessed using the Chinese version of M.D. Anderson Symptom Inventory (MDASI) . At the same time, Kappa test was used to analyze the consistency of reports of patients, their main caregivers and nursing staff to the 13 adverse reactions of chemotherapy in the scale.Results:After the second chemotherapy cycle, except for the two adverse reactions of fatigue and distress, the severity of other adverse reactions reported by the patients was not statistically significantly different compared with the records of the main caregivers and nursing staff ( P>0.05) . The incidence of fatigue, distress, sleep disturbance, nausea and dry mouth reported by the patients was higher than that recorded by the primary caregivers and nursing staff, and the differences were statistically significant ( P<0.05) . The patients showed good consistency with main caregivers in 10 aspects such as appetite loss, shortness of breath, sleep disturbance, vomiting, pain, nausea, dry mouth, drowsiness, forgetfulness and numbness ( P<0.05) . The patients showed good consistency with the nursing staff in 9 aspects such as appetite loss, shortness of breath, vomiting, pain, nausea, dry mouth, lethargy, forgetfulness and numbness ( P<0.05) . The main caregivers showed good consistency with the nursing staff in 10 aspects such as appetite loss, distress, shortness of breath, vomiting, pain, nausea, dry mouth, lethargy, forgetfulness and numbness ( P<0.05) . After the fourth chemotherapy cycle, the self-reported severities of fatigue, distress, sleep disturbance and sadness of patients were higher than those recorded by the main caregivers and nursing staff, and the differences were statistically significant ( P<0.05) . The incidence of fatigue, distress, sleep disturbance, sadness and dry mouth reported by patients were higher than those recorded by the main caregivers and nursing staff, and the differences were statistically significant ( P<0.05) . The patients showed good consistency with the primary caregivers in 8 aspects such as appetite loss, shortness of breath, vomiting, pain, nausea, dry mouth, forgetfulness and numbness ( P<0.05) , and they showed good consistency with the nursing staff in 7 aspects such as appetite loss, vomiting, pain, nausea, dry mouth, forgetfulness and numbness ( P<0.05) . The primary caregivers showed good consistency with the caregivers in 8 aspects such as appetite loss, sleep disturbance, vomiting, pain, nausea, dry mouth, forgetfulness and numbness ( P<0.05) . Conclusions:Nursing staff and the main caregivers of patients underestimate the incidence and severity of chemotherapy-related adverse reactions in patients with stomach neoplasms. Simple nursing records cannot accurately reflect the patients' chemotherapy symptoms, so self-reports of patients should be considered as one of the reference data.
