Design,numerical simulation and experimental study of novel oxygenator
10.19745/j.1003-8868.2024044
- VernacularTitle:一种新型氧合器的设计、数值仿真与实验研究
- Author:
Ming-Hao YUE
1
;
Shi-Yao ZHANG
;
Ji-Nian LI
;
Hui-Chao LIU
;
Zi-Hua SU
;
Ya-Wei WANG
;
Zeng-Sheng CHEN
;
Shi-Hang LIN
;
Jin-Yu LI
;
Ya-Ke CHENG
;
Yong-Fei HU
;
Cun-Ding JIA
;
Ming-Zhou XU
Author Information
1. 北京航天长峰股份有限公司,北京 100039
- Keywords:
ECMO;
oxygenator;
vascular access;
numerical simulation
- From:
Chinese Medical Equipment Journal
2024;45(3):23-28
- CountryChina
- Language:Chinese
-
Abstract:
Objective To design a novel oxygenator to solve the existing problems of extracorporeal membrane oxygenation(ECMO)machine in high transmembrane pressure difference,low efficiency of blood oxygen exchange and susceptibility to thrombosis.Methods The main body of the oxygenator vascular access flow field was gifted with a flat cylindrical shape.The topology of the vascular access was modeled in three dimensions,and the whole flow field was cut into a blood inlet section,an inlet buffer,a heat exchange zone,a blood oxygen exchange zone,an outlet buffer and a blood outlet section.The oxygenator was compared with Quadrox oxygenator by means of ANSYS FLUENT-based simulation and prototype experiments.Results Simulation calculations showed the oxygenator designed was comparable to the clinically used ones in general,and gained advantages in transmembrane pressure difference,blood oxygen exchange and flow uniformity.Experimental results indicated that the oxygenator behaved better than Quadrox oxygenator in transmembrane pressure difference and blood oxygen exchange.Conclusion The oxygenator has advantages in transmem-brane pressure difference,temperature change,blood oxygen ex-change and low probability of thrombosis.[Chinese Medical Equipment Journal,2024,45(3):23-28]