Focusing on clinical activity score of thyroid eye disease suitable for Chinese population
10.3760/cma.j.cn115989-20240418-00112
- VernacularTitle:关注适合中国人群的甲状腺眼病临床活动性评分方法
- Author:
Chaoyu LEI
1
;
Hui WANG
;
Jing SUN
;
Huifang ZHOU
Author Information
1. 上海交通大学医学院附属第九人民医院眼科 上海市眼眶病眼肿瘤重点实验室 教育部视觉系统疾病医药基础研究创新中心，上海 200011
- Keywords:
Thyroid eye disease;
Clinical activity score;
Atlas
- From:
Chinese Journal of Experimental Ophthalmology
2024;42(11):977-982
- CountryChina
- Language:Chinese
-
Abstract:
Thyroid eye disease (TED) is an orbital disease closely associated with thyroid disorders, with 25%-50% of patients with diffuse toxic goiter (Graves Disease) developing secondary TED, which can lead to blindness and disability and significantly impair patients' visual function and quality of life.Activity staging is a crucial assessment index for TED and is essential for clinical evaluation, treatment planning, and prognosis.The Clinical Activity Score (CAS) is currently the most widely used method for this purpose both domestically and internationally.To improve the accuracy and consistency of CAS evaluations, the European Group of Graves' Orbitopathy (EUGOGO) recommended the use of a CAS scoring atlas in the TED guidelines.However, existing atlases are primarily based on Caucasians.Considering the anatomical differences in the orbit between Chinese and Caucasians and the resulting divergent ocular characteristics, there is a need for a comprehensive interpretation of the CAS scoring details in the current guidelines.This should be followed by further refinement to tailor the CAS scoring criteria to Chinese patients with TED.Such measures will standardize the operational methods and judgment criteria of CAS scoring in China, thereby providing a reliable basis for the accurate diagnosis and treatment of the disease.
