Research progress in the relationship between structural and biomechanical changes of the optic disc in myopic eyes and optic neuropathy
10.13389/j.cnki.rao.2024.0155
- VernacularTitle:近视视盘结构及生物力学改变与视神经病变关系的研究进展
- Author:
Xia ZHANG
1
;
Ziqi MENG
;
Haoru LI
;
Reihua WEI
Author Information
1. 300384 天津市,天津医科大学眼科医院、眼视光学院、眼科研究所,国家眼耳鼻喉疾病临床医学研究中心天津市分中心,天津市视网膜功能与疾病重点实验室
- Keywords:
myopia;
optic disc;
biomechanics;
optic neuropathy
- From:
Recent Advances in Ophthalmology
2024;44(10):818-822
- CountryChina
- Language:Chinese
-
Abstract:
Myopia-associated optic neuropathy has become an important cause of visual impairment with the increasing prevalence of myopia in recent years.However,the mechanisms for its occurrence and development are still in primary re-search.Numerous studies suggest that structural changes in the optic disc that often occur in the progress of myopia may be closely associated with optic neuropathy.The optic disc is stretched mechanically with the growth of the axial length,resulting in changes in its morphology,biomechanics and blood flow,which may induce optic neuropathy.This review summarized the relationship between pathophysiological histostructural and biomechanical changes,including scleral con-nective tissue remodeling,peripapillary atrophy,tilt and torsion of optic disc,and thinning of lamina cribrosa and peripapil-lary scleral margin,and optic neuropathy in myopic patients,hoping to provide a new insight for early detection and pre-vention of myopia-associated optic neuropathy.
