Papular Xanthoma in a Child.
- Author:
Ji Young SEO
1
;
Moon Seub SHIN
;
Soo Jin KIM
;
Sik HAW
;
Seong Hyun KIM
Author Information
1. Department of Dermatology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea. shkimderm@paik.ac.kr
- Publication Type:Case Report
- Keywords:
Children;
Papular xanthoma
- MeSH:
Adult;
Child*;
Dermis;
Diagnosis;
Giant Cells;
Humans;
Infant;
Lower Extremity;
Male;
Periodic Acid;
Skin;
Skin Diseases;
Xanthomatosis*
- From:Korean Journal of Dermatology
2014;52(2):129-132
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Papular xanthoma is a rare normolipemic xanthomatous skin disease that primarily occurs in adults. While this rare disorder has been documented in children before, all but one case reported in the literature involved a normal lipid profile. The skin lesions of adult papular xanthoma appear to be persistent, whereas in children they generally self-heal within 1~5 years. Here, we describe a typical case of papular xanthoma in a 22-month-old boy who presented with numerous reddish-yellow papulonodules, 2~8 mm in diameter, mainly on the face, but also on the upper and lower extremities, and trunk, for 15 months. The lipid profile was normal, and histological studies showed a diffuse monomorphous infiltrate of foamy cells, with some Touton giant cells, in the dermis. The foamy cells stained positive for Cluster of Differentiation (CD) 68, and the Periodic Acid Schiff (PAS) stain was negative. These findings are consistent with the diagnosis of papular xanthoma.
