Cheilitis Granulomatosa Successfully Treated with Minocycline.
- Author:
Hyojin KIM
1
;
Jeong Nan KANG
;
In Ho PARK
;
So Young JUNG
;
Jung Eun SEOL
;
Ho Suk SUNG
Author Information
1. Department of Dermatology, Busan Paik Hospital, College of Medicine, Inje University, Busan, Korea. derma09@hanmail.net
- Publication Type:Case Report
- Keywords:
Cheilitis granulomatosa;
Minocycline
- MeSH:
Adrenal Cortex Hormones;
Cheilitis*;
Dermis;
Granuloma;
Hydroxychloroquine;
Lip;
Melkersson-Rosenthal Syndrome*;
Methods;
Metronidazole;
Minocycline*;
Rare Diseases
- From:Korean Journal of Dermatology
2014;52(2):133-135
- CountryRepublic of Korea
- Language:English
-
Abstract:
Cheilitis granulomatosa, a rare disease of unknown cause, is characterized clinically by recurrent or persistent swelling of the lip. Histopathologically, the dermis contains non-necrotizing granuloma, lymphangiectasia, and perivascular lymphocytic infiltration. Treatment of cheilitis granulomatosa is difficult, due to its unknown etiology. Several therapeutic methods have been attempted, including systemic and intralesional corticosteroids, oral metronidazole, non-steroidal anti-inflammatory drugs (NSAIDs), hydroxychloroquine, and surgical reduction, but unfortunately no treatment method has yet proven reliable.
