Application of the simplified postnatal growth and retinopathy of prematurity screening criteria in detecting severe retinopathy of prematurity
10.13389/j.cnki.rao.2024.0119
- VernacularTitle:《产后生长和早产儿视网膜病变(G-ROP)筛查标准》(简化版)在严重早产儿视网膜病变筛查中的应用
- Author:
Bolin DENG
1
;
Wentao DONG
Author Information
1. 610072 四川省成都市,四川省医学科学院·四川省人民医院(电子科技大学附属医院)眼科
- Keywords:
retinopathy of prematurity;
postnatal growth;
screening;
criteria
- From:
Recent Advances in Ophthalmology
2024;44(8):623-626
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the accuracy of simplified postnatal growth and retinopathy of prematurity(G-ROP)screening criteria in detecting severe retinopathy of prematurity(ROP)and compare it with the current screening cri-teria and the recommended screening criteria in this study.Methods A total of 1 286 premature infants screened for ROP at Sichuan Provincial People's Hospital from January 2015 to December 2022 were retrospectively selected.All patients under-went routine fundus examination using the binocular indirect ophthalmoscope or wide-angle digital pediatric retinal imaging system(Retcam)after pupil dilation.Detailed clinical data,such as birth weight(BW),gestational age(GA),gender,and fundus examination results,were collected.Fundus lesions were diagnosed and treated according to the Chinese Guidelines for Screening Retinopathy of Prematurity(2014)(the screening criteria were BW＜2 000 g or GA＜32 weeks).The simplified G-ROP screening criteria were defined as BW＜1 051 g or GA＜28 weeks.The recommended screening criteria were defined as BW≤1 500 g or GA≤30 weeks.The performance of screening criteria for detecting severe ROP was analyzed using the receiv-er operating characteristic(ROC)curve.Results A total of 302 infants(23.5％,302/1 286)met the simplified G-ROP screening criteria,of which 159(52.6％,159/302)had severe ROP.A total of 134 infants(45.7％,134/293)with severe ROP were misdiagnosed.The ROC analysis results showed that the sensitivity and specificity of the simplified G-ROP screening cri-teria for detecting severe ROP were 37.54％and 88.52％,respectively,with an area under the curve(AUC)of 0.630.The sensitivity and specificity for detecting severe ROP according to the Chinese Guidelines for Screening Retinopathy of Prematu-rity(2014)were 98.9％and 18.4％,respectively,with an AUC of 0.587.The sensitivity and specificity for detecting severe ROP according to the recommended screening criteria were 91.8％and 47.0％,respectively,with an AUC of 0.694.The rec-ommended screening criteria had reduced the number of screened infants by 380(29.5％,380/1 286)compared to the Chi-nese Guidelines for Screening Retinopathy of Prematurity(2014),and only 7(2.4％,7/293)with severe ROP were misdiag-nosed.Conclusion The simplified G-ROP screening criteria have poor accuracy in detecting severe ROP.Adjusting the cri-teria to BW≤1 500 g or GA ≤30 weeks is more suitable for the screening strategy of ROP in China.
