Observation on the efficacy of subthreshold micropulse laser photocoagula-tion in the treatment of central serous chorioretinopathy based on multimodal imaging classification
10.13389/j.cnki.rao.2024.0102
- VernacularTitle:阈值下微脉冲激光治疗多模式成像分类的中心性浆液性脉络膜视网膜病变的疗效观察
- Author:
Bei XIAO
1
,
2
;
Yanping SONG
;
Ming YAN
;
Ya YE
;
Zhen HUANG
;
Cong CHEN
;
Yumeng DENG
Author Information
1. 510515 广东省广州市,南方医科大学第一临床医学院
2. 430070 湖北省武汉市,中国人民解放军中部战区总医院眼科
- Keywords:
central serous chorioretinopathy;
micropulse laser photocoagulation;
subretinal fluid;
multimodal ima-ging
- From:
Recent Advances in Ophthalmology
2024;44(7):531-535
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the efficacy of 577 nm subthreshold micropulse laser photocoagulation(SMLP)on central serous chorioretinopathy(CSC)and explore the baseline characteristics and prognostic features of multimodal ima-ging-based CSC.Methods A retrospective analysis was conducted on 44 patients(46 eyes)with CSC diagnosed at the Ophthalmology Department of the General Hospital of Central Theater Command,PLA from June 2017 to May 2022.The pa-tients were classified into the simple CSC group(23 eyes)and the complex CSC group(23 eyes)based on the multimodal imaging classification.All patients underwent 577 nm SMLP treatment.The best corrected visual acuity(BCVA)and cen-tral macular thickness(CMT)of patients between the two groups were compared before treatment and at 1,3 and 6 months after treatment.The intra-group and inter-group changes and the complete absorption rate of subretinal fluid(SRF)in CSC eyes of patients between the two groups were assessed before treatment and at 6 months after follow-up.Results The BCVA of patients in the simple CSC group significantly improved at 6 months after treatment compared with the base-line(P=0.010);the BCVA of patients in the complex CSC group significantly improved at 3 and 6 months after treatment compared with the baseline(both P＜0.01).The CMT of patients in the simple CSC group was significantly lower than the baseline at 1,3,and 6 months after treatment(all P＜0.05);the CMT of patients in the complex CSC group was signifi-cantly lower than the baseline at 1 and 6 months after treatment(both P＜0.05);the change in CMT from baseline after 6 months of treatment for simple CSC was(-163.74±88.10)μm,the change in CMT from baseline after 6 months of treat-ment for complex CSC was(-71.96±164.30)μm,and the difference between the two groups was statistically significant(P=0.023).During the follow-up period,the number of eyes with persistent SRF in the simple CSC group was significant-ly lower than that in the complex CSC group(P＜0.05).The complete absorption rate of SRF at 6 months after treatment in the simple CSC group was greater than that in the complex CSC group(P＜0.05).Conclusion The prognosis of sim-ple CSC treated with 577 nm SMLP is better than that of complex CSC,and the new multimodal imaging classification has a certain value in predicting the prognosis of CSC after SMLP.
