Meta-analysis of risk factors for lung infection in patients with craniocerebral injury after tracheotomy
10.3760/cma.j.issn.1674-2907.2020.03.013
- VernacularTitle:颅脑损伤患者气管切开术后肺部感染危险因素的Meta分析
- Author:
Lei YE
1
;
Rui QU
;
Aiqin ZHANG
Author Information
1. 南京大学医学院附属金陵医院(东部战区总医院)重症医学科 210002
- Keywords:
Craniocerebral injury;
Meta-analysis;
Tracheotomy;
Risk factor;
Lung infection
- From:
Chinese Journal of Modern Nursing
2020;26(3):350-355
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the risk factors for lung infection in patients with craniocerebral injury after tracheotomy through Meta-analysis and provide a scientific reference for its prevention. Methods The inclusion and exclusion criteria were determined and the search strategies were designed. Two researchers independently searched both English and Chinese databases such as Cochrane Library, EMBASE, PubMed, CNKI, Wanfang and VIP (taking brain injury, craniocerebral injury, traumatic brain injury, tracheotomy, lung infection, pulmonary infection, risk factor, influencing factor and promotive factor as the key words) for literatures published since the databases were built to April 28th, 2019. RevMan 5.3 was used to analyze the data after the quality of literatures were assessed. Results Totally 9 articles were included, including 2112 patients with craniocerebral injury. Meta-analysis showed that diabetes [OR=3.36, 95％CI(2.49, 4.54),P< 0.01], use of hormones [OR=2.52,95％CI(1.83, 3.45),P< 0.01], Glasgow Coma Scale (GCS) score [OR=2.92,95％CI(1.95, 4.37),P< 0.01], hypoproteinemia [OR=3.18,95％CI(2.20, 4.60), P< 0.01], aspiration [OR=3.18, 95％CI(2.24, 4.51),P < 0.01], smoking [OR=1.87,95％CI(1.16, 3.00), P < 0.01], non-irrigable tracheal cannula [OR=2.54, 95％CI(1.71, 3.77),P<0.01]and tracheotomy time (>7 d) [OR=2.32, 95％CI (1.42, 3.79);P< 0.01]were the influencing factors for lung infection in patients with craniocerebral injury after tracheotomy. Conclusions Existing evidence shows that combined with diabetes, use of hormones, high GCS score, hypoalbuminemia, occurrence of aspiration, use of non-irrigable tracheal cannula, smoking, tracheotomy time > 7 d were independent risk factors for lung infection in patients with craniocerebral injury.
