Research progress on the protective effect of remote ischemic preconditioning on perioperative acute kidney injury and its mechanism

VernacularTitle:远隔缺血预处理对围手术期急性肾损伤的保护作用及机制研究进展
Author: Ziying TAO ^{1
,

2} ; Erliang KONG ; Yang ZHANG ; Xudong FENG
Author Information

1. 新乡医学院,河南新乡 453003
2. 中国人民解放军联勤保障部队第九八八医院麻醉科,河南郑州 450042
Keywords: remote ischemic preconditioning; acute kidney injury; renal protection
From: Journal of Xinxiang Medical College 2024;41(11):1086-1089,1096
CountryChina
Language:Chinese
Abstract: Acute kidney injury(AKI)is a common perioperative complication,which is associated with an increased incidence rate of other postoperative complications and death risk of the patients.Remote ischemic preconditioning(RIPC)performs multiple transient ischemia/reperfusion cycles at remote sites far from the target organs to enhance the tolerance of target organs to oxidative stress.A large number of animal experiments have shown that RIPC can improve kidney function,alleviate AKI,and increase the survival rate of AKI patients.However,there is still controversy about the mechanism of RIPC in alleviating AKI in clinical studies.In this article,the research progress on the role and mechanism of RIPC in renal protection in recent years is reviewed,in order to provide a reference for further exploration of perioperative renal protection strategies and mechanisms.