Research progress of osteoarthritis pain mechanism and related traditional Chinese medicine treatment

VernacularTitle:骨关节炎疼痛机制及相关中药治疗研究进展
Author: Zhu JIN ¹ ; Gaoqing LIU ; Wenbo XU ; Linfeng LIU ; Wenxin ZHANG ; Lihe WANG
Author Information

1. 河南中医药大学骨伤学院,河南郑州 450000
Keywords: osteoarthritis; pain; signaling pathway; traditional Chinese medicine treatment
From: Journal of Xinxiang Medical College 2024;41(10):996-1000
CountryChina
Language:Chinese
Abstract: Osteoarthritis(OA)is the most common degenerative disease in clinical practice.Joint pain is the main manifestation of OA,and in severe cases,it can lead to joint deformity.The main pathological changes include destruction of articular cartilage,synovitis,thickening of subchondral bone,bone redundancy,degeneration of articular ligaments,and enlargement of articular periosteum.Clinicopathological changes and pain degrees in OA patients vary from person to person,and treatment options vary from person to person.Clinically,non-steroidal anti-inflammatory drugs are used to treat the pain of OA patients now,but the effect is not ideal,and long-term use of these drugs will bring obvious toxic and side effects.Traditional Chinese medicine obtains good results in relieving the pain of OA patients.Therefore,this paper reviews the research on traditional Chinese medicine treatment and pain mechanisms of OA,with a view to providing ideas and references for clinical relief of pain in OA patients.