Application and advances in multi-omics analysis in non-traumatic osteonecrosis of femoral head
10.7683/xxyxyxb.2024.06.018
- VernacularTitle:多组学分析在非创伤性股骨头坏死中的应用现状和研究进展
- Author:
Mingyue SHI
1
,
2
;
Faqiang LU
Author Information
1. 大连大学附属中山医院医学检验中心,辽宁 大连 116001
2. 大连大学中山临床学院,辽宁 大连 116001
- Keywords:
non-traumatic osteonecrosis of femoral head;
genomics;
transcriptomics;
proteomics;
metabolomics;
multi-omics
- From:
Journal of Xinxiang Medical College
2024;41(6):596-600
- CountryChina
- Language:Chinese
-
Abstract:
Non-traumatic osteonecrosis of the femoral head(NONFH)is a disabling disease of the hip joint and severe-ly affects the quality of life of patients.The complex pathogenesis of NONFH has not yet been investigated clearly,so clinical diagnosis and treatment are limited.In recent years,multi-omics,as a high-throughput detection and analysis technique,has played an essential role in unraveling the characteristics of NONFH and aiding the diagnosis of the disease.This article reviews the latest applications of and advances in multi-omics including genomics,transcriptomics,proteomics and metabolomics in NONFH,so as to provide new ideas for further exploration of the pathogenesis of NONFH.
