Effectiveness and safety of drug coated balloon in patients with acute ST segment elevation myocardial infarction during interventional therapy
10.3969/j.issn.1008-0074.2024.03.08
- VernacularTitle:药物涂层球囊对急性ST段抬高型心肌梗死患者介入治疗的有效性和安全性
- Author:
Yu-Bin HUANG
1
;
Min CAI
;
Jin-Zao CHEN
Author Information
1. 莆田市第一医院心内科,福建莆田 351100
- Keywords:
Myocardial infarction;
Angioplasty,balloon,coronary;
Drug-coated balloon;
Drug-eluting stents
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2024;33(3):294-298
- CountryChina
- Language:Chinese
-
Abstract:
Objective:This study aims to evaluate the effectiveness and safety of drug coated balloon(DCB)and drug elu-ting stent(DES)during primary percutaneous coronary intervention(PCI)in patients with ST segment elevation myocardi-al infarction(STEMI).Methods:Clinical data of 142 STEMI patients who underwent emergency PCI in our hospital from Jan 2018 to Dec 2021 were retrospectively analyzed.According to intervention strategy,patients were divided into obser-vation group(n=62,DCB therapy)and control group(n=80,DES therapy).Incidence rates of target lesion revascular-ization and major adverse cardiovascular events(MACE)within one week,left ventricular ejection fraction(LVEF),left ventricular end-diastolic diameter(LVEDd)and incidence rate of slow-flow after PCI,above indexes(except slow-flow),late lumen loss(LLL)and incidence of hemorrhea etc.within nine-month follow-up were compared between two groups.Results:There were no significant difference in postoperative LVEDd,LVEF,incidence rates of slow-flow,target lesion revascularization and MACE within one week between two groups,P＞0.05 all.After nine-month follow-up,there were no significant difference in LLL[0.25(0.16,0.50)mm vs.0.30(0,0.82)mm],incidence rates of target lesion revascularization(6.3％vs.4.8％),MACE(31.7％vs.33.9％)and hemorrhea(8.5％vs.3.2％)be-tween control group and observation group,P＞0.05 all.Conclusion:In patients with ST segment elevation myocardial in-farction undergoing emergency percutaneous coronary intervention,short-and long-term prognosis of drug coated bal-loon are not inferior to those of drug eluting stent,which is safe and effective.
