Relationship between hypertension history and long-term coronary adverse prognosis in patients with acute coronary syndrome
10.3969/j.issn.1008-0074.2024.03.01
- VernacularTitle:高血压史与急性冠脉综合征患者远期冠脉不良预后的关系
- Author:
Meng-Ya DONG
1
;
Chen-Bo XU
;
Juan ZHOU
;
Zu-Yi YUAN
Author Information
1. 陕西省人民医院心血管内二科,陕西西安 710068
- Keywords:
Acute coronary syndrome;
Hypertension;
Myocardial ischemia;
Risk factors
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2024;33(3):261-264
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the relationship between hypertension history and long-term coronary adverse prognosis in patients with acute coronary syndrome(ACS).Methods:The study was a retrospective,single-center,observational research.A total of 385 patients,who admitted in Department of Cardiology of First Affiliated Hos-pital of Xi'an Jiaotong University from January 2013 to February 2014,diagnosed as ACS and received coronary an-giography(CAG),were continuously collected.Ischemic events were defined as revascularization,in-stent throm-bosis,in-stent restenosis and active angina.Kaplan-Meier survival curve and Cox regression analysis were used to determine the relationship between hypertension history and long-term coronary adverse prognosis in ACS pa-tients.Results:The 385 patients were divided into hypertension history ≤1 year group(n=201)and hypertension history＞1 year group(n=184)according to the median of hypertension history.After follow-up of 2.6(2.3,2.8)years,39 cases(19.4％)and 46 cases(25.0％)suffered from ischemic events in hypertension history ≤1 year group and hypertension history＞1 year group respectively.Kaplan-Meier survival curve analysis revealed that the incidence rate of ischemic events in hypertension history＞1 year group was significantly higher than that of hyper-tension history ≤1 year group(x2=4.675,P=0.031).After adjusting possible confounding factors,multivariable Cox regression analysis indicated that hypertension history remained an independent risk factor of ischemic events in ACS patients(HR=1.033,95％CI 1.008-1.057,P=0.008).Conclusion:Hypertension history is an independent risk factor for long-term ischemic events in patients with acute coronary syndrome.And the risk of ischemic e-vents is significantly increasing with the longer hypertension history.
