Wernicke's encephalopathy after haploid hematopoietic stem cell transplantation: 3 cases report and literature review
10.3760/cma.j.cn121090-20231214-00309
- VernacularTitle:单倍体造血干细胞移植后Wernicke脑病3例报告并文献复习
- Author:
Qianqian XIAO
1
;
Xiaolin YU
;
Xiaochen SONG
;
Wenjun LI
;
Lei DENG
;
Yixi HOU
;
Fang ZHOU
Author Information
1. 山东第二医科大学临床医学院，潍坊 261053
- From:
Chinese Journal of Hematology
2024;45(8):781-784
- CountryChina
- Language:Chinese
-
Abstract:
Case 1: A 27-year-old female with ALK-positive anaplastic large cell lymphoma/leukemia; Case 2: A 27-year-old male with acute myeloid leukemia; Case 3: A 56-year-old male with myelodysplastic syndrome. These three patients underwent haploid hematopoietic stem cell transplantation and experienced severe oral mucosal inflammation, nausea, vomiting, diarrhea, and other symptoms over a long period, which significantly restricted eating. Neurological and psychiatric symptoms appeared at 50, 38, and 50 days following transplantation, respectively. The diagnosis of Wernicke encephalopathy was made by head magnetic resonance imaging, whereas the condition improved significantly after intravenous infusion of vitamin B 1.
