Fertility-sparing Surgery for Ovarian Non-invasive Low-grade Serous Carcinoma and Literature Review
10.3969/j.issn.1674-9081.2016.04.009
- VernacularTitle:卵巢非侵袭性低级别浆液性癌保留生育功能手术五例及文献复习
- Author:
Lei LI
1
;
Feng-Zhi FENG
;
Rong FAN
;
Wen-Jia LOU
;
Yuan LI
;
Jia-Li TONG
;
Xiao-Yan CHANG
;
Ling-Ya PAN
Author Information
1. 中国医学科学院 北京协和医学院 北京协和医院妇产科
- Keywords:
ovarian borderline tumor;
micropapillary variant of serous borderline tumor/ovarian non-invasive low-grade serous carcinoma;
fertility-sparing surgery
- From:
Medical Journal of Peking Union Medical College Hospital
2016;7(4):285-289
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the characteristics of fertility-sparing surgery for non-invasive low-grade serous carcinoma ( LGSC) of the ovary .Methods All the histologically diagnosed patients of non-inva-sive LGSC who admitted to Peking Union Medical College Hospital and received fertility -sparing surgeries between January 2015 and June 2015 were reviewed and their clinicopathological characteristics , surgical procedures , and follow-up results were retrospectively analyzed .Results Totally five cases of non-invasive LGSC receiving fertili-ty-sparing surgeries were reviewed .Their median age was 29 years (range, 24-34 years).One case received laparotomy and four received laparoscopies; four cases received ovarian cystectomy and one received emergency unilateral adnexectomy for the affected and necrotic ovary because of acute torsion .One case was diagnosed at In-ternational Federation of Gynecology and Obstetrics ( FIGO) stage IB, and the other four were at stage IA .All the five cases received no further therapy after the surgery .The median follow-up period was 7 months ( range , 6-12 months ) .No case relapsed so far .One case conceived naturally and both the mother and the fetus were in good condition .Conclusions For non-invasive LGSC patients , there are many unresolved issues in aspects of spare of fertility , conception after fertility-sparing surgeries , recurrence , and follow-up.Although the possibility to spare the ovary is supported by this study for young non-invasive LGSC patients , long-term prognosis ( inclu-ding fertility and survival ) needs to be observed in further follow-up.
