Clinical characteristics of POEMS syndrome initially diagnosed as increased extravascular volume load: a single-center retrospective study
10.3760/cma.j.cn121090-20231117-00264
- VernacularTitle:以血管外容量负荷增大为首诊表现的POEMS综合征临床特征：单中心回顾性研究
- Author:
Ting ZHANG
1
;
Jue ZHANG
;
Xuxing SHEN
;
Yuanyuan JIN
;
Run ZHANG
;
Jianyong LI
;
Lijuan CHEN
Author Information
1. 南京医科大学第一附属医院，江苏省人民医院血液科，南京 210029
- From:
Chinese Journal of Hematology
2024;45(7):694-697
- CountryChina
- Language:Chinese
-
Abstract:
POEMS syndrome is a rare plasma cell dysplasia. Its clinical manifestations include polyneuropathy, monoclonal protein, increased extravascular volume load, endocrinopathy, organomegaly and skin changes. The complex and atypical symptoms at presentation make early diagnosis challenging due to multiple system involvement. Peripheral neuropathy, limb numbness, is the most common initial symptom of this disease. However, case reports of increased extravascular volume load are rare. This article collected and analyzed the clinical data of two groups of patients with different initial symptoms (increased extravascular volume load and limb numbness). The clinical characteristics and treatment responses were summarized.
