Comparison of predictive power of different dementia risk assessment tools for Alzheimer's disease in Chinese elders
10.3760/cma.j.issn.1674-2907.2019.29.008
- VernacularTitle:不同痴呆风险评估工具对中国老年居民阿尔茨海默病预测价值的比较研究
- Author:
Shasha PAN
1
;
Jing SUN
Author Information
1. 北京大学护理学院 100191
- Keywords:
Alzheimer's disease;
Aged;
Dementia;
Risk assessment;
Forecasting
- From:
Chinese Journal of Modern Nursing
2019;25(29):3744-3749
- CountryChina
- Language:Chinese
-
Abstract:
Objective? To compare the predictive and applicable power of 3 dementia risk assessment tools for Alzheimer's disease in Chinese elders. Methods? In this case-control study, totally 80 elderly patients with Alzheimer's disease hospitalized in 5 hospitals in Beijing from May 2013 to August 2018 were selected by convenient sampling as the case group, while 80 elders with normal cognitive function were randomly selected as the control group from the same region. Clinical data of both groups were collected, and the subjects' morbidity risk of Alzheimer's disease was assessed using Barnes Model, Australian National University Alzheimer's Disease Risk Index (ANU-ADRI) and Chinese Alzheimer's Disease Risk Assessment Model (C-ADRA). The predictive power of different assessment tools was thus compared. Results? There was significant difference in family history of dementia, craniocerebral injury, hearing disorder, depression, lifestyle as well as some physiological and biochemical criteria between case and control groups. The accuracy, sensitivity and specificity of C-ADRA in predicting Alzheimer's disease in Chinese elders was better than that of Barnes and ANU-ADRI models. Conclusions? C-ADRA has a better predictive power for Alzheimer's disease in Chinese elders. Targeted prevention may be provided for patients according to the results of risk assessment, thus promising a guarantee for the prevention and control of Alzheimer's disease in clinical nursing and prevention.
