A Case of Granulomatous Pancreatitis Caused by Syphilis.
- Author:
Won Gyu CHOI
1
;
Chang Won LEE
;
Hong Joon PARK
;
In Seok BAEK
;
Jang Won KIM
;
Duk Whan JANG
;
Seung Il WOO
;
Soon Chul BAE
;
Jae Joong BAIK
;
Hak San KIM
Author Information
1. Department of Internal Medicine, National Medical Center, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Granuloma;
Pancreatitis;
Syphilis
- MeSH:
Diarrhea;
Fatigue;
Female;
Germany;
Granuloma;
Humans;
Jaundice;
Korea;
Middle Aged;
Pancreas;
Pancreatitis*;
Rare Diseases;
Sarcoidosis;
Syphilis*;
Vasculitis
- From:Korean Journal of Medicine
1997;52(5):696-701
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Granulomatous pancreatitis is a granulomatous inflammatory disease of the pancreas and can he described only in infectious granulomas and pancreatic involvement by systemic granulomatosis. Sarcoidosis, isolated pancreatic involvement without systemic granulomatosis or a manifestation of systemic sarcoidosis, is more common cause of granulo-mataus pancreatitis than infectious granuloma. There has been some reports show a characteristic histological finding of the pancreatic involvement of sarcoidasis. Noncaseating granuloma is thought to be the characteristic finding of pancreatic sarcoidosis. But granulomatous pancreatitis caused by syphilis in a syrnptomatic patient is a very rare disease and, till now, to our knowledge, only a case was reported in 1987, Germany. We experienced a 55-year-old female patient with granulomatous pancreatitis caused by tertiary syphilis who presented as a recent onset jaundice, diarrhea, fatigue and vague epigastric discomfort. Radical pancreaticoduo-denectomy was performed, which showed noncaseating granulomatous pancratitis with vasculitis. To our knowledge, this is the first case of granulomatous pancreatitis caused by syphilis in Korea. We hereby report a case of granulomatous pancreatitis caused by syphilis with a brief review of literature.