Menstrual Cylc icity Change in Ovair an Aging
10.3969/j.issn.1674-9081.2016.02.001
- VernacularTitle:卵巢衰老过程中的月经改变
- Author:
Zhong HE
1
;
Shou-Qing LIN
;
Rong CHEN
;
Ying CHEN
;
Hong-Lian GAO
;
Zheng-Lai WU
Author Information
1. 中国医学科学院 北京协和医学院 继续教育学院
- Keywords:
ovarian aging;
length of menstrual cycle;
menstrual period;
menstrual volume
- From:
Medical Journal of Peking Union Medical College Hospital
2016;7(2):81-87
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the alterations of each menstrual factor in ovarian aging .Methods The data were obtained from one-year observation of a prospective cohort involving 323 healthy women in the age of 30-54 years in a community in Beijing .Menstrual diary was kept and serum level of follicle-stimulating hor-mone ( FSH) was tested .The participants were divided into groups based on age , FSH level , and stages of repro-ductive aging.Alterations of length of menstrual cycle (LMC), length of menstrual period , and menstrual volume were analyzed in each group .Results Age:the mean LMC extended after the age of 40 years, obviously after 48, and peaked with (67.04 ±36.77) days in≥52-year-old group.The mean length of menstrual period did not vary much with age .However , the variation of mean length of menstrual period gradually increased with age after 44 years old, peaked in 50-to 51-year-old group.The menstrual volume scores were approximately stable between 38 and 47 years of age , with a peak of (45.06 ±93.54) in48 -to 49-year-old group and a minimum of (15.87 ± 13.81) in≥52-year-old group.FSH level:LMC increased with elevation of FSH levels .There was no signifi-cant difference in the mean length of menstrual period among FSH level groups , but the variation of length of menstrual period was maximum in 2040U /Lgroup .Stages of reproductive aging:the length of menstrual period and menstrual volume scores among each stage showed no statistically significant difference ( P>0.05 ) .Co nclusions The LMC altered significant-ly in ovarian aging , which could be used as staging criteria of reproductive aging .The length of menstrual period and menstrual volume are also showing some characteristic changes , possibly of some clinical values .
