Hemophagocytic syndrome secondary to invasive NK cell leukemia and T-cell lymphoma treated with the modified MINE protocol: report of three cases and literature review
10.3760/cma.j.cn121090-20231115-00261
- VernacularTitle:改良MINE方案治疗侵袭性NK细胞白血病和T细胞淋巴瘤继发噬血细胞综合征3例并文献复习
- Author:
Di WU
1
;
Miaojing LI
;
Yao LI
;
Tongxia LU
;
Luyao FU
;
Pengcheng HE
Author Information
1. 西安交通大学第一附属医院血液内科，西安 710061
- From:
Chinese Journal of Hematology
2024;45(6):599-601
- CountryChina
- Language:Chinese
-
Abstract:
Lymphoma-associated hemophagocytic syndrome is aggressive with rapid progression, particularly in NK/T cell lymphoma. The MINE regimen is a salvage treatment for aggressive non-Hodgkin lymphoma. In our center, the modified MINE regimen was applied to treat three patients with hemophagocytic syndrome secondary to aggressive NK cell leukemia and T-cell lymphoma. The modified MINE regimen showed good efficacy against NK/T cell lymphoma, control of the inflammatory state of secondary hemophagocytic syndrome, and good tolerability.
