Meta-analysis of the intervention effects of early ambulation on acquired weakness in intensive care unit patients with mechanical ventilation
10.3760/cma.j.issn.1674-2907.2019.24.013
- VernacularTitle:早期活动在ICU机械通气患者获得性衰弱干预应用效果的Meta分析
- Author:
Bing LIANG
1
;
Li ZHANG
;
Ke ZHANG
;
Jianhong XI
;
Ping YAN
Author Information
1. 新疆医科大学护理学院
- Keywords:
Intensive care unit;
Respiration,artificial;
Early ambulation;
Early exercise;
ICU acquired weakness;
ICU acquired muscle weakness
- From:
Chinese Journal of Modern Nursing
2019;25(24):3091-3096
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo systematic analyze the intervention effects of early ambulation on ICU acquired weakness(ICU-AW) in ICU patients. MethodsThe Cochrane Library, PubMed, EMBASE, MEDLINE, CBM, CNKI and Wanfang database were searched via computer for randomized controlled trials on early ambulation to prevent ICU-AW in ICU patients from the data base establishment date to February 10th, 2019.After screening literature, extracting data and evaluating the quality of literature, Meta-analysis was carried out with RevMan 5.3 software. ResultsFinally, 11 randomized controlled trials were included. Meta-analysis results showed that the incidence of ICU-AW was RR=0.52, 95%CI was (0.41, 0.66); muscle strength (MRC-score) WMD=8.08, 95%CI was (6.27, 9.81); Barthel index WMD=18.24, 95%CI was (7.27, 29.2); mechanical ventilation time was WMD=-1.29, 95%CI was (-1.96, -0.61); ICU hospitalization time was MD=-1.81, 95%CI was (-2.78,-0.84); total hospitalization time WMD=-3.39, 95%CI (-5.91, -0.88). ConclusionsBased on the present evidence, early ambulation can reduce the incidence of ICU-AW, improve the activity of daily life ability of patients,shorten the duration of mechanical ventilation, length of stay in ICU and hospital, which is worthy of clinical application.
