Research progress of intratumoral bacteria in digestive system neoplasms
10.3760/cma.j.cn115610-20240507-00239
- VernacularTitle:肿瘤内菌群在消化系统肿瘤中的研究进展
- Author:
Lin JIANG
1
;
Yuhan ZHANG
;
Lingxiao ZHANG
;
Ying HUANG
;
Yingbin LIU
Author Information
1. 上海理工大学健康科学与工程学院，上海 200093
- Keywords:
Digestive system neoplasms;
Intratumoral microbiome;
Intratumoral bac-teria;
Anti-tumor therapy;
Prognosis
- From:
Chinese Journal of Digestive Surgery
2024;23(6):868-875
- CountryChina
- Language:Chinese
-
Abstract:
Intratumoral bacteria are a group of bacteria that exist within tumors and make up the tumor microenvironment. They play a significant role in tumorigenesis and progression, as well as in influencing the response of tumors to chemotherapy and immunotherapy through various mechanisms. This article primarily discusses the sources and mechanisms of action of intratumoral bacteria, with a specific focus on their composition and functions in the digestive system. Further-more, it explores the potential application of intratumoral bacteria in anti-tumor therapy, aiming to provide valuable references for future clinical use.
