Advances in prognostic value of inflammatory markers in pancreatic neuroendocrine neoplasms
10.3760/cma.j.cn115610-20240328-00182
- VernacularTitle:炎症标志物在预测胰腺神经内分泌肿瘤预后中的应用进展
- Author:
Chaoyu PANG
1
;
Xin GAO
;
Zhiyao FAN
;
Hanxiang ZHAN
Author Information
1. 山东大学齐鲁医院胰腺外科，济南 250012
- Keywords:
Pancreatic neopalsms;
Neuroendocrine neoplasm;
Inflammatory marker;
Prognosis;
Advances
- From:
Chinese Journal of Digestive Surgery
2024;23(5):680-684
- CountryChina
- Language:Chinese
-
Abstract:
Pancreatic neuroendocrine neoplasm (pNEN) is highly heterogeneous, and the prognosis varies among tumors of different stages and grades. However, there is lacking high pro-gnostic predictors with sensitivity and specificity. Inflammation plays a pivotal role in the occurrence and development of different tumors, various inflammatory markers such as neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, lymphocyte-monocyte ratio are of great significance in the diagnosis, treat-ment, and prognosis of tumors. Several studies have demonstrated that inflammatory markers are associated with poor prognosis and can serve as predictive factors for tumor prognosis. The authors summarize recent advances in the researches focused on the prognostic value of inflamma-tory markers in pNEN, in order to provide novel insights for clinical decision-making of pNEN.
