Continuous electroencephalogram monitoring in the diagnosis of neonatal seizures in hypoxic-ischemic encephalopathy and the evaluation of the efficacy of antiseizure medications
10.3760/cma.j.issn.1673-4912.2024.10.003
- VernacularTitle:新生儿缺氧缺血性脑病中连续脑电监测对惊厥的诊断及抗发作药物疗效的评估
- Author:
Xiuying FANG
1
;
Jian MAO
Author Information
1. 中国医科大学附属盛京医院神经功能科，沈阳 110004
- Keywords:
Neonatal hypoxic-ischaemic encephalopathy;
Neonatal seizures;
Electroencephalo- gram monitoring;
Antiseizure medication
- From:
Chinese Pediatric Emergency Medicine
2024;31(10):733-737
- CountryChina
- Language:Chinese
-
Abstract:
Neonatal hypoxic-ischemic encephalopathy (HIE) stands as one of the most prevalent brain injuries during the neonatal stage,a condition whose salient clinical symptom includes seizures.The extent of the seizure burden is intimately tied to the gravity of the brain injury.Continuous video electroencephalogram (vEEG) monitoring is the gold standard in diagnosing neonatal seizures.It plays a pivotal role in identifying neonatal seizures and distinguishing them from non-seizure motor phenomena,thereby ensuring a precise diagnosis.The classification of seizures in neonate with HIE is dichotomized into electrical-clinical seizures and electrical-only seizures,based on the presence or absence of clinical manifestations.Among these,electrical seizures are the most prevalent type.The American Clinical Neurophysiological Society advocates for a minimum of 24-hour EEG monitoring for infants with HIE to guarantee prompt and efficient treatment.Antiseizure medication(ASM) is a crucial therapy for neonatal HIE seizure episodes,underscoring the importance of administering it promptly to children with neonatal seizures.When utilizing ASM,it is imperative to implement continuous vEEG monitoring to fine-tune the dosage and medication duration,thus shortening patient stays and diminishing the necessity for ASM upon discharge.
