Retrospective analysis of ten patients with severe human Boca virus pneumonia required mechanical ventilation
10.3760/cma.j.issn.1673-4912.2024.06.009
- VernacularTitle:需机械通气的儿童重症博卡病毒肺炎十例临床分析
- Author:
Shuangjun LIU
1
;
Feng HUO
;
Jun LIU
;
Yimu FAN
;
Zhezhe ZHANG
;
Xiao LIU
;
Shuo WANG
;
Jie WU
;
Quan WANG
Author Information
1. 国家儿童医学中心 首都医科大学附属北京儿童医院急诊科 100045
- Keywords:
Mechanical ventilation;
Human Boca virus;
Severe pneumonia
- From:
Chinese Pediatric Emergency Medicine
2024;31(6):449-454
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To summarize the clinical characteristics of children with severe pneumonia requiring mechanical ventilation due to human Boca virus infection.Methods:Clinical data of children with severe human Boca virus pneumonia required mechanical ventilation who were admitted to the emergency intensive care unit at Beijing Children's Hospital Affiliated to Capital Medical University from October 2022 to June 2023 were retrospectively analyzed.Results:A total of ten children with human Boca virus pneumonia required mechanical ventilation were included,including seven males with a median age of 21.5(10.0-42.0) months and six children less than two years old.Six patients were admitted to hospital in the fall of 2022 and four were in the summer of 2023.All cases had cough,wheezing and fever.The wheezes could be heard in all patients admitted to hospital for physical examination.Respiratory sounds were reduced in six cases,and moist crackles were heard in two cases.Two patients had thrush.One patient with bronchial lavage culture showed streptococcus pneumoniae and staphylococcus aureus.One patient had human herpesvirus type 6 infection on day 5 of the course of disease,and one child had rhinovirus.There was no evidence of co-infection in the remaining five cases.All patients were given mechanical ventilation for respiratory failure,and the median mechanical ventilation time was 85 (46-165) hours.Each patient was examined by bronchoscope for 1-3 times.Bronchoscopy manifested endobronchial inflammation,mucosal swelling,increased secretions (10/10),mucous thrombus formation (8/10) and scattered necrotic epithelium (4/10).All patients were discharged after improvement and the median length of administration was 9 (6-14) days.Conclusion:Human Boca virus is one of the important pathogens of severe pneumonia in children,with severe cough,wheezing and feve,which can lead to endobronchial trachea inflammation,easy to form mucous embolus and mucosal necrosis.In severe cases,mechanical ventilation and bronchoscopy are required,and most of them have good prognosis.
