Incidence and influencing factors of post-extubation dysphagia among patients with mechanical ventilation:a meta-analysis
10.3760/cma.j.issn.1674-2907.2019.17.011
- VernacularTitle:机械通气患者拔管后吞咽障碍发生率及影响因素的Meta分析
- Author:
Yingli HU
1
;
Mengxin CAI
;
Donglei SHI
Author Information
1. 中国医学科学院北京协和医院中心治疗室 100730
- Keywords:
Meta-analysis;
Respiration,artificial;
Post-extubation dysphagia
- From:
Chinese Journal of Modern Nursing
2019;25(17):2158-2163
- CountryChina
- Language:Chinese
-
Abstract:
Objective? To systematically analyze the incidence and influencing factors of post-extubation dysphagia (PED) among patients with mechanical ventilation. Methods? Observational studies on PED were systematically retrieved in PubMed, CIHNAL, Cochrane Library, WanFang data, China National Knowledge Infrastructure (CNKI) and VIP. We screened literatures, extracted data and evaluated the literature quality. The Stata14.0 was used to meta-analysis. Results? A total of 1 356 literatures were retrieved and 8 of them were included, 5 literatures on cohort study and 3 on cross-sectional study. Totals of 2 384 research objects were included and 553 of them were with PED. Meta-analysis showed that the incidence of PED was 36% (95% CI: 23%-50%), the rates of PED patients with intubation time ≥48 h and ＜48 h were 46% (95%CI: 40%-53%) and 6% (95%CI: 5%-7%) respectively. The independent influencing factors of PED were the intubation time and ages. Subgroup analysis revealed that the ages(OR=2.18,95%CI:1.42～3.34) was the influencing factor among patients with intubation time ＜48 h, but intubation time could not be determined;the ages (OR=1.02, 95%CI: 1.00-1.05) and intubation time (OR=1.28, 95%CI: 1.08-1.52) were the influencing factors among patients with intubation time ≥48 h. Publication bias analysis showed that the included literatures were with no significant bias and with credible results. Conclusions? We should pay attention to problems existing in PED among patients with mechanical ventilation particularly in patients with intubation time ≥48 h and old ages, so as to promote early detection and early intervention of PED.
