Effects of short-term structural psychological education on depression and immunity in patients with Barcelona clinic liver cancer B or C stage hepatocellular carcinoma
10.3760/cma.j.issn.1674-2907.2019.14.011
- VernacularTitle:短期结构式心理教育对巴塞罗那临床肝癌分期为B/C期的肝癌患者抑郁情绪及免疫功能的影响
- Author:
Xinhua ZHAO
1
;
Lingyun ZHAO
;
Jueling WEI
;
Mei LUO
;
Xuemei YOU
Author Information
1. 广西医科大学附属肿瘤医院肝胆外科
- Keywords:
Hepatocellular neoplasms;
Depression;
Structural psychological intervention;
Immunity
- From:
Chinese Journal of Modern Nursing
2019;25(14):1764-1768
- CountryChina
- Language:Chinese
-
Abstract:
Objective? To explore the effects of short-term structural psychological education on depression and immunity in patients with Barcelona clinic liver cancer B or C stage (BCLC-B/C) hepatocellular carcinoma. Methods? Totally 210 patients with BCLC-B/C hepatocellular carcinoma who were admitted in the Department of Hepatological Surgery, Guangxi Medical University Affiliated Tumor Hospital from June 2016 to March 2018 were selected by convenient sampling and divided into the non-depression group (n=79) and the depression group (n=131) according to Hospital Anxiety and Depression Scale-Depression (HADS-D) and Patient Health Questionnaire (PHQ-9). Patients in the depression group were randomly divided into the intervention group (n=66) and the control group (n=65). Patients in the non-depression group and the depression-control group received conventional nursing care, while patients in the depression-intervention group received short-term structural psychological education on the basis of conventional nursing care. HADS-D, PHQ-9 and cytoimmunity indexes were used to evaluate the effects of intervention. Results? The HADS-D and PHQ-9 scores of the depression-intervention group were lower than those of the control group on day 30 postoperatively(P＜0.01). The CD3+, CD3+CD4+, CD3+CD4+/CD3+CD8+ levels of the depression-intervention group were higher than those of the depression-control group on day 30 postoperatively (P＜0.05). Conclusions? Short-term structural psychological education can effectively improve the depression and immunity in patients with BCLC-B/C,which is worth promoting in clinical practice.
