Analysisof HPV infection gene subtypes in the gynecology outpatient clinic of a hospital in Huadu district,Guangzhou
10.3969/j.issn.1671-332X.2024.05.040
- VernacularTitle:广州市花都区某医院妇科门诊HPV感染基因亚型情况分析
- Author:
Siyi LI
1
;
Hanbin HU
;
Xueping LUO
;
Weiwei HUANG
;
Dongyun ZHU
;
Xinyi CHEN
Author Information
1. 广州市中西医结合医院 广东广州 510800
- Keywords:
Human papilloma virus;
Genotype;
Hybridization
- From:
Modern Hospital
2024;24(5):803-805,809
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To analyze the gene subtypes and characteristics of human papilloma virus(HPV)infection among women attending outpatient and physical examination centers at our hospital.Methods We utilized Polymerase Chain Reaction(PCR)combined with reverse dot hybridization to detect 28 HPV gene subtypes.Results HPV infection rate among the women was 24.15％.The five most prevalent high-risk(HR)and low-risk(LR)HPV gene subtypes were HPV 52,16,53,58,39,and HPV 61,81,54,42,44,respectively.Single and double infections accounted for 68.97％and 20.72％,with no signifi-cant difference found in the combination of multiple infection types.When stratified by age,the highest HPV infection rate was found among the group aged ≤25 years,followed by the group aged ≥66 years and then the group aged 56-65 years.This pattern of HPV infection rates across age groups revealed an approximate U-shaped curve.Conclusion The majority of female HPV in-fections in Huadu district are single infections,primarily affecting young and middle-aged women.HPV gene subtypes exhibit the characteristics of population or region-specific distribution.The overall infection rate of HPV is 24.15％,with the most common types being 52,16,and 53.The three peak age groups for HPV infection ranges are ≤25 years,56-65 years,and ≥66 years.
