Analysis of correlation between colorectal adenoma and serum lipid level
10.3969/j.issn.1672-2159.2024.02.002
- VernacularTitle:结直肠腺瘤与血脂水平相关性分析:一项单中心回顾性研究
- Author:
Qun LIANG
1
,
2
;
Su-Dong LIU
;
Rui-Qiang WENG
;
Xiao-Dong GU
;
Bo-Ying LIU
Author Information
1. 524002 广东医科大学
2. 514000 广东医科大学梅州临床医学院
- Keywords:
Colorectal cancer;
Adenoma;
Serum lipid;
Risk factor
- From:
Modern Interventional Diagnosis and Treatment in Gastroenterology
2024;29(2):122-125,134
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between serum lipid profiles and colorectal adenomas,and to benefit the prevention of colorectal cancer.Methods This study retrospectively analyzes the serum lipid profiles and clinical parameters of 2,960 patients who were diagnosed with colorectal adenomas,and 3,156 individuals without colorectal adenomas in Meizhou People's Hospital from May 2018 to May 2020.The association between serum lipid profiles and colorectal adenoma was evaluated by Logistic regression analysis.Results It was observed that the serum levels of total cholesterol(TC),triglyceride(TG),low density lipoprotein cholesterol(LDL-C)and apoliprotein B(ApoB)were significantly elevated in patients with colorectal adenomas.Dyslipidemia was more prevalent in adenoma cases than in controls.The Logistic regression analysis suggested that serum TC and TG levels were positively associated with the occurrence of colorectal adenomas.Conclusion Elevated serum TG and TC levels are independent risk factors for adenoma,and adenoma patients with elevated serum TG and TC levels may be more likely to develop high-risk adenoma.
