Research advances on in-situ cell electrospinning and its application in wound repair
10.3760/cma.j.cn501225-20231123-00204
- VernacularTitle:原位细胞电纺技术及其在创面修复中的应用研究进展
- Author:
Huazhen LIU
1
;
Yi ZHANG
;
Chuang GAO
;
Chunxiang LU
;
Zilong GUO
;
Wenbin SUN
;
Shichu XIAO
;
Yuanyuan LIU
Author Information
1. 上海大学医学院，上海 200444
- Keywords:
Nanofibers;
Tissue scaffolds;
Tissue engineering;
In-situ cell electrospinning;
Wound repair
- From:
Chinese Journal of Burns
2024;40(7):694-698
- CountryChina
- Language:Chinese
-
Abstract:
Currently, there are limited strategies for convenient and rapid wound repair in clinical practice. In recent years, in-situ cell electrospinning (IS-CE) technology, developed from in-situ electrospinning (IS-E) technology, has emerged. IS-CE technology involves encapsulating living cells within micro-nanofibers to construct living fibrous tissue scaffolds in situ, making some progress in wound repair applications. However, this technology still faces limitations such as low cell survival rate and poor fiber stability. This article provides a comprehensive review on the current status of both IS-E and IS-CE technologies, as well as the application of IS-CE technology in wound repair. In addition, the advantages, limitations, and improvement methods of IS-CE technology applied in wound treatment are emphatically discussed, aiming to provide insights for its application in tissue engineering and wound repair.
