Research advances on the mechanism of circadian rhythm genes in wound healing
10.3760/cma.j.cn501225-20230831-00071
- VernacularTitle:昼夜节律基因在创面愈合中的作用机制研究进展
- Author:
Ying TENG
1
;
Fang QI
;
Guangchao XU
;
Dali WANG
Author Information
1. 遵义医科大学附属医院烧伤整形外科,遵义 563003
- Keywords:
Circadian rhythm;
Genes;
Skin;
Wound healing
- From:
Chinese Journal of Burns
2024;40(7):689-693
- CountryChina
- Language:Chinese
-
Abstract:
The healing after skin injury is a dynamic process of the interaction of various cells, cytokines, and extracellular matrix, and the abnormality of any link will affect the speed and quality of wound healing. Circadian rhythm is a spontaneous periodic oscillation cycle in organisms, which plays an important role in maintaining homeostasis and regulating physiological activities. Studies have shown that circadian rhythm genes play a key role in wound healing. This review summarizes the effects of circadian rhythm genes on different stages of wound healing and its possible mechanism of action, in order to provide a new perspective for wound healing and provide theoretical basis for formulating more effective treatment strategies for refractory wounds.