Research advances on the roles of metabolic remodeling and protein acylation modification in keloids

VernacularTitle:代谢重塑及蛋白酰化修饰在瘢痕疙瘩中的作用研究进展
Author: Zelan MU ¹ ; Yongxiang TENG ; Jian ZHANG ; Nan BAI ; Yanjie FU
Author Information

1. 山东第二医科大学临床医学院，潍坊　261053
Keywords: Keloid; Metabolism; Proteins; Acylation
From: Chinese Journal of Burns 2024;40(6):589-593
CountryChina
Language:Chinese
Abstract: Keloid is a common skin disease, and the mechanism of its occurrence is not fully understood. There is evidence to show that multiple factors such as genetics, race, age, gender, hormones, infection, immunity, and oxidative stress, etc. may be related to the occurrence of keloids. Metabolic remodeling and protein acylation modification, as two important biological processes, play important roles in various skin related diseases. Based on this, this article reviews the roles of metabolic remodeling and protein acylation modification in keloids and the interrelationship between the two biological processes, and explores the application prospects of targeting the two biological processes in the prevention and treatment of keloids.