Research advances on the role of adipokines in diabetic peripheral arterial diseases
10.3760/cma.j.cn501225-20230724-00017
- VernacularTitle:脂肪因子在糖尿病外周血管病变中的作用研究进展
- Author:
Ting LU
1
;
Amin LIU
;
Qihui JIN
;
Ling ZHANG
Author Information
1. 浙江大学医学院附属第二医院基础和转化研究中心，杭州 310009
- Keywords:
Diabetes mellitus;
Peripheral vascular diseases;
Adipokines;
Drug interactions
- From:
Chinese Journal of Burns
2024;40(5):495-500
- CountryChina
- Language:Chinese
-
Abstract:
Peripheral arterial disease is one of the common complications of diabetes. At present, the pathogenesis of diabetic peripheral arterial diseases is not completely clear, and there is a lack of effective treatment methods and drugs. Adipokines have profound impact on the occurrence and development of diabetes mellitus and its complications, and are directly or indirectly involved in the progression of diabetic peripheral arterial diseases. Different adipokines may inhibit or promote the occurrence of vascular diseases with the mechanisms that are complex and controversial. Adipokines are expected to be a new target for the treatment of diabetic peripheral arterial disease, which is worthy of further study. This article mainly reviews the relationship between some common adipokines and new adipokines and diabetic vascular disease, aiming to provide new methods for the clinical treatment of diabetic peripheral arterial disease.
