Dynamic changes and nursing strategies of chemotherapy-induced nausea and vomiting in patients of newly diagnosed with non-small cell lung cancer
10.3760/cma.j.issn.1674-2907.2019.01.015
- VernacularTitle:初诊非小细胞肺癌患者化疗所致恶心呕吐的动态变化及护理对策
- Author:
Xiaoyue GAO
1
;
Fen GU
;
Lili HOU
Author Information
1. 上海交通大学医学院附属第九人民医院护理部
- Keywords:
Carcinoma,non-small-cell lung;
? Nausea;
? Vomiting;
? Chemotherapy
- From:
Chinese Journal of Modern Nursing
2019;25(1):68-72
- CountryChina
- Language:Chinese
-
Abstract:
Objective? To descriptively analyze the dynamic changes of chemotherapy-induced nausea and vomiting in patients of newly diagnosed with non-small cell lung cancer (NSCLC) during the first chemotherapy cycle after first chemotherapy with gemcitabine plus cisplatin (GP), in order to provide targeted prevention and nursing during the peak period. Methods? A total of 165 NSCLC patients from Shanghai Pulmonary Hospital from January to December 2017 were recruited by convenience sampling method. Chemotherapy-induced nausea and vomiting (CINV) were followed up on the 3rd, 5th, 7th, 14th, and 21st day of chemotherapy, and CINV grades were recorded. Results? In the first chemotherapy cycle, the incidence of nausea was 90.3% (149/165), mostly in grade 2, and the peak period was the 3rd to the 7th day after chemotherapy, while the incidence of vomiting was 50.9% (84/165), mostly in grade 1, and the peak period was the 4th to the 6th days. Conclusions? During the first chemotherapy cycle of GP regimen in patients newly diagnosed with NSCLC, the peak period of CINV was the 3rd to the 7th day, and lasted 3 to 5 days. According to the time window and duration of high incidence of nausea and vomiting, medical staff can intervene in a timely manner to prevent or reduce the occurrence of nausea and vomiting.
