Recent advances of skin tissue engineering based on three-dimensional bioprinting technology
10.3760/cma.j.cn501225-20230131-00029
- VernacularTitle:基于三维生物打印技术的皮肤组织工程研究进展
- Author:
Yang LI
1
;
Taotao XI
;
Dongmei ZHENG
;
Jun GE
;
Xiao'e LUO
;
Lin WANG
Author Information
1. 西安外事学院医学院，精准抗衰健康产品研发与转化陕西省高校工程研究中心，西安 710077
- Keywords:
Skin transplantation;
Tissue engineering;
Three-dimensional bioprinting;
Skin model
- From:
Chinese Journal of Burns
2023;39(11):1096-1100
- CountryChina
- Language:Chinese
-
Abstract:
The fundamental purpose of tissue-engineered skin development is to restore the skin barrier function of patients with severe skin injury, and this kind of product has become an ideal substitute for skin transplantation in clinic at present. With the development of three-dimensional bioprinting technology, the three-dimensional skin models constructed with complex structures such as skin appendages are also becoming increasingly mature. The stable three-dimensional skin model is widely used in skin physiological and pathological research, cosmetic safety and efficacy evaluation, and alternating animal experiments. In this paper, we introduced the three-dimensional bioprinting technology in categories, summarized the types of bio-inks commonly used for skin model construction, reviewed the recent advances of three-dimensional bioprinting technology applied in the field of skin tissue engineering, and explored and prospected the future directions of its research development and application fields.
