Research advances of skin tissue engineering scaffolds loaded with adipose-derived stem cells in wound repair
10.3760/cma.j.cn501225-20221123-00502
- VernacularTitle:负载脂肪干细胞的皮肤组织工程支架在创面修复中的研究进展
- Author:
Wei LI
1
;
Weishi KONG
;
Yulu BAO
;
Yu SUN
Author Information
1. 海军军医大学第一附属医院烧伤外科，全军烧伤研究所，中国医学科学院烧伤暨烧创复合伤救治关键技术创新单元，上海 200433
- Keywords:
Tissue engineering;
Skin;
Adipose-derived stem cells;
Scaffold material;
Wound repair
- From:
Chinese Journal of Burns
2023;39(11):1090-1095
- CountryChina
- Language:Chinese
-
Abstract:
Tissue engineered skin is widely used in the treatment of refractory wounds such as severe burn wounds and diabetic wounds. Seed cells and scaffold materials are the key elements for constructing tissue engineered skin. Adipose-derived stem cells have gradually become an important choice of seed cells in tissue engineered skin due to their advantages of low immunogenicity and multi-directional differentiation potential. Scaffold material is a vital part of skin tissue engineering. The modification of single material and preparation of composite materials are becoming the main research directions of the construction of skin tissue engineering scaffolds. This paper introduced the application of various kinds of skin tissue engineering scaffolds loaded with adipose-derived stem cells in wound repair in recent years, and summarized the advantages and disadvantages in using various scaffold materials to the construction of skin tissue engineering scaffolds, in order to provide new ideas for the development of tissue engineered skin loaded with adipose-derived stem cells.
