Research advances on application of pancreatic stone protein in the early diagnosis of sepsis
10.3760/cma.j.cn501225-20221120-00498
- VernacularTitle:胰石蛋白在脓毒症早期诊断中应用的研究进展
- Author:
Ting HE
1
;
Wei LIU
;
Chuan'an SHEN
Author Information
1. 解放军总医院第四医学中心烧伤整形医学部，北京 100048
- Keywords:
Sepsis;
Lithostathine;
Infection;
Diagnosis
- From:
Chinese Journal of Burns
2023;39(10):985-988
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis is a severe life-threatening syndrome characterized by an abnormal host response to infection that can rapidly evolve into septic shock and multiple organ failure. Treatment of sepsis depends on early identification and diagnosis as well as adequate and timely anti-infection and multi-organ functional support. In recent years, pancreatic stone protein has been widely studied as a new biomarker for sepsis. Existing evidence shows that compared with the commonly used inflammatory markers in clinical practice, pancreatic stone protein has higher sensitivity and specificity in the diagnosis of sepsis. It enables the early diagnosis of sepsis and assessment of the severity of septic patients to a certain extent. This article reviews the characteristics, biological functions, diagnostic features, and clinical application of pancreatic stone protein.
