Research progress of biomaterials with ordered micro-nano structure in wound repair
10.3760/cma.j.cn501225-20221017-00455
- VernacularTitle:含有序微纳米结构的生物材料用于创面修复的研究进展
- Author:
Yibing TAO
1
;
Keqing SHI
;
Jian XIAO
Author Information
1. 温州医科大学附属第一医院创面修复与再生中心，转化医学实验室，温州 325000
- Keywords:
Wound healing;
Tissue engineering;
Nanofibers;
Biocompatible materials;
Groove;
Micro-nano structure
- From:
Chinese Journal of Burns
2023;39(9):896-900
- CountryChina
- Language:Chinese
-
Abstract:
Many injury-causing factors, including burns and surgery, etc., can lead to the destruction of structure and function of skin. Suitable wound dressing or implant is the material basis to promote wound healing and regeneration. Biomaterials with micro-nano structure can affect cell behavior, promote orderly growth of cell in accordance with the structure. Their application in wound healing can promote angiogenesis, regulate immune response, and reduce scar area. In recent years, the application of biomaterials with ordered micro-nano structure in tissue engineering has attracted extensive attention. This paper introduces the structure and preparation methods of several biomaterials with ordered micro-nano structure, and focuses on how the surface microstructure of biomaterials affects the process of wound healing and its molecular mechanism, in order to find and develop medical biomaterials that are closer to the skin tissue structure for clinical wound treatment.
