Research advances in the treatment of keloid with glucocorticoids
10.3760/cma.j.cn501225-20230602-00198
- VernacularTitle:糖皮质激素治疗瘢痕疙瘩的研究进展
- Author:
Yinghong SU
1
;
Wenzheng XIA
;
Xin HUANG
;
Ruoqing XU
;
Khoong YIMIN
;
Tao ZAN
Author Information
1. 上海交通大学医学院附属第九人民医院整复外科,上海 200011
- Keywords:
Keloid;
Glucocorticoids;
Receptors, glucocorticoid;
Drug resistance
- From:
Chinese Journal of Burns
2023;39(9):886-890
- CountryChina
- Language:Chinese
-
Abstract:
As a first-line classical drug, glucocorticoids are used in most combination treatment regimens of keloid. However, there are issues such as poor treatment efficacy and recurrence of keloid after keloid was treated with glucocorticoids, which seriously affect the therapeutic effect. In recent years, many studies have explored the factors influencing the efficacy of glucocorticoids in treating keloid and the action mechanism of glucocorticoids from different perspectives. Based on this, this paper reviews the mechanism and the factors influencing the efficacy of glucocorticoids in treating keloid, and explores ways to improve the treatment efficacy of glucocorticoids, aiming to provide thoughts for improving glucocorticoid-related diagnostic and therapeutic strategies.