Research advances on the mechanism of oral mucosal stem cells in promoting wound healing

VernacularTitle:口腔黏膜干细胞促进创面愈合的机制研究进展
Author: Zhiru WEI ¹ ; Yan DONG ; Guangshuai LI ; Linbo LIU
Author Information

1. 郑州大学第一附属医院整形外科，郑州　450052
Keywords: Wound healing; Cytokines; Oral mucosal stem cells; Pluripotency
From: Chinese Journal of Burns 2023;39(5):496-500
CountryChina
Language:Chinese
Abstract: Wound healing is a complex process that requires the participation of multiple cells and cytokines. During the process of wound healing, abnormality in any stage of the process may lead to the development of a chronic refractory wound. Research has confirmed that various stem cells can promote wound healing, but some stem cells are limited in clinical application due to difficulties in isolation, susceptibility to apoptosis, ethical and legal issues. Oral mucosal stem cells (OMSCs) can avoid the above problems. This type of stem cells has the characteristics of embryonic stem cells, immune regulatory ability, and strong homogeneity. It plays an important role in the process of scarless oral wound healing, and has become a research hotspot in promoting wound healing and reducing scar formation. This article reviews the research on the mechanism, clinical application prospects, and current problems of OMSCs in promoting wound healing.