Research advances on the mechanism of nerve regeneration-related protein in skin fibrosis

VernacularTitle:神经再生相关蛋白在皮肤纤维化中的作用机制研究进展
Author: Wei CHEN ¹ ; Guangchao XU ; Zhonglu HUANG ; Li CHEN ; Kaiyu NIE
Author Information

1. 遵义医科大学附属医院烧伤整形外科，遵义　563003
Keywords: Skin; Cicatrix; Fibrosis; Nerve regeneration-related protein
From: Chinese Journal of Burns 2023;39(5):491-495
CountryChina
Language:Chinese
Abstract: The healing process after skin injury is a dynamic process of interaction between various cells, cytokines, and extracellular matrix. Fibrosis is one of the main ways of skin injury repair. The process of fibrosis involves the regulation of many factors. Studies have shown that nerve regeneration-related protein (NREP) plays a key role in the fibrosis of skin tissue and organs. Based on the mechanism of skin fibrosis, this paper discusses the construction of tertiary structure of NREP, summarizes the effects of NREP and different cells in the skin on skin fibrosis and the research progress of mechanism of NREP in skin fibrosis, thus providing new ideas for the treatment of skin fibrosis diseases.