Research advances on the mechanism of circular RNA in diabetic wound healing
10.3760/cma.j.cn501225-20220727-00317
- VernacularTitle:环状RNA在糖尿病创面愈合中的作用机制研究进展
- Author:
Yule NONG
1
;
Yehui LYU
Author Information
1. 上海健康医学院创面防治研究所，上海 201318
- Keywords:
Diabetes mellitus;
Wound healing;
Circular RNA;
Mechanism of action
- From:
Chinese Journal of Burns
2023;39(5):487-490
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, a large number of studies have shown that non-coding RNAs play an important role in wound healing process. Among them, studies on the mechanism of circular RNA (circRNA) have shown that circRNA is closely related to the proliferation of cells related to wound healing, such as endothelial progenitor cells and keratinocytes, and circRNA is also involved in the chronic wound healing process. Based on the introduction of the related concept of circRNA, this paper focuses on the possible regulatory mechanism of circRNA in different stages of diabetic wound healing and summarizes the potential role of circRNA in the process of diabetic peripheral vascular atherosclerosis, aiming to explore the in-depth molecular mechanism and clinical significance of circRNA in diabetic wound healing process, and provide reference for further research.
